Structural Biology

basic-crystallography-diagrams   rm01_01_311_robo_proj1_clon1_g0_0000g0000077_001_070122_02_03_01_hf_99_032_001_rdi

Structural Biology is the study of life and biological phenomena at the molecular and atomic level. The goals of structural biology include developing a comprehensive understanding of the molecular shapes and forms embraced by biological macromolecules and extending this knowledge to understand how different molecular architectures are used to perform the chemical reactions that are central to life. (See protein crystal images below)

Protein xtals   xtalss

Xray_Diagram   Crystal_Pin

To get a window into Structural Biology, see examples below of various proteins structures which were solved by x-ray crystallography.

Apoptosis factor

Image: Structure of the Apoptosome-Procaspase-9 – CARD Complex

The structure of truncated human apolipoprotein A-I (PDB code 1AV1) is the major protein component of high density lipoprotein.

Image: The structure of human apolipoprotein A-I, the major protein component of high density lipoprotein.

Annotated_Theoretical_Model_of_Bound_Tetrameric_Lac_Repressor

Image: Tetrameric LacI binds two operator sequences and induces DNA looping

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